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About Enolase
Enolase is an enzyme from
Lyase family (EC 4.2.1.11), with molecular weight within 40-50kDa range for monomer (biological structure - dimer), that catalyze conversion of 2-phosphoglycerate to phosphoenolpyruvate (PEP) with subsequent removing of water molecule. The overall reaction can be written as 2-Phosphoglycerate <=> Phosphoenolpyruvate + H2O
Systematic name for Enolase is 2-phospho-D-glycerate hydro-lyase (phosphoenolpyruvate-forming), but in literature other names are also acceptable: 14-3-2-protein; phosphoenolpyruvate hydratase; 2-phosphoglycerate dehydratase; 2-phosphoglycerate dehydratase; nervous-system specific enolase; 2-phosphoglycerate enolase; 2-phospho-D-glycerate hydro-lyase; 2-phosphoglyceric dehydratase and γ-enolase.
Enolase IUBMB Enzyme Nomenclature hierarchy
Enolase classification on the basis of recommendations of Nomenclature Committee of the International Union of Biochemistry and Molecular Biology (NC-IUBMB):
- EC 4 Lyases
- EC 4.2 Carbon-oxygen lyases
- EC 4.2.1 Hydro-Lyases (dehydratases)
- EC 4.2.1.11 2-phospho-D-glycerate hydro-lyase (phosphoenolpyruvate-forming)
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